Journal of Comprehensive Pediatrics

Published by: Kowsar

Serum Interleukin 13 Level in Steroid Sensitive Nephrotic Syndrome

Nahid Mamizadeh 1 , Hasan Otukesh 1 , Rozita Hoseini 1 and Fereshteh Moshfegh 1 , *
Authors Information
1 Nephrology Department, Ali Asghar Hospital, Iran University of Medical Sciences, Tehran, IR Iran
Article information
  • Journal of Comprehensive Pediatrics: August 2017, 8 (3); e12765
  • Published Online: August 31, 2017
  • Article Type: Research Article
  • Received: May 7, 2017
  • Accepted: July 31, 2017
  • DOI: 10.5812/compreped.12765

To Cite: Mamizadeh N, Otukesh H, Hoseini R, Moshfegh F. Serum Interleukin 13 Level in Steroid Sensitive Nephrotic Syndrome, J Compr Ped. 2017 ; 8(3):e12765. doi: 10.5812/compreped.12765.

Copyright © 2017, Journal of Comprehensive Pediatrics. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Methods
3. Results
4. Discussion
  • 1. Kimata H, Fujimoto M, Furusho K. Involvement of interleukin (IL)-13, but not IL-4, in spontaneous IgE and IgG4 production in nephrotic syndrome. Eur J Immunol. 1995; 25(6): 1497-501[DOI][PubMed]
  • 2. Neuhaus TJ, Wadhwa M, Callard R, Barratt TM. Increased IL-2, IL-4 and interferon-gamma (IFN-gamma) in steroid-sensitive nephrotic syndrome. Clin Exp Immunol. 1995; 100(3): 475-9[PubMed]
  • 3. Yap HK, Cheung W, Murugasu B, Sim SK, Seah CC, Jordan SC. Th1 and Th2 cytokine mRNA profiles in childhood nephrotic syndrome: evidence for increased IL-13 mRNA expression in relapse. J Am Soc Nephrol. 1999; 10(3): 529-37[PubMed]
  • 4. Van Den Berg JG, Aten J, Annink C, Ravesloot JH, Weber E, Weening JJ. Interleukin-4 and-13 promote basolateral secretion of H+ and cathepsin L by glomerular epithelial cells. Am J Physiol Renal Physiol. 2002; 282(1)-33
  • 5. Wei CL, Cheung W, Heng CK, Arty N, Chong SS, Lee BW, et al. Interleukin-13 genetic polymorphisms in Singapore Chinese children correlate with long-term outcome of minimal-change disease. Nephrol Dial Transplant. 2005; 20(4): 728-34[DOI][PubMed]
  • 6. Lai KW, Wei CL, Tan LK, Tan PH, Chiang GS, Lee CG, et al. Overexpression of interleukin-13 induces minimal-change-like nephropathy in rats. J Am Soc Nephrol. 2007; 18(5): 1476-85[DOI][PubMed]
  • 7. Reiser J, von Gersdorff G, Loos M, Oh J, Asanuma K, Giardino L, et al. Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest. 2004; 113(10): 1390-7[DOI][PubMed]
  • 8. Tain Y. Implications of serum TNF-β and IL-13 in the treatment response of childhood nephrotic syndrome. Cytokine. 2003; 21(3): 155-9[DOI]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments